In a dystopian future Japan, sisters Ami and Yoshie struggle to survive in the lawless Ishinari District. Having sold their bodies to support their parents, they attempt to make a living as an idol duo. Their performance attracts the attention of Matsukata, a notorious hitman. This encounter forces the sisters to recognize their bond while they fight against Aoyama Dharma, the ruthless leader of an organ harvesting ring. Outmatched by her forces, Ami and Yoshie receive experimental weaponry, transforming them into deadly killers.