The Powerpuff Girls

The Powerpuff Girls (2016 – 2019)

2016 • 3 seasons • Comedy, Animation • TV-Y7-FV

On August 10, 2026

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6,189.8 Attention Score

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Episode 21 — Sister Sitter

Season 1 • The Powerpuff Girls

Released: 2016-06-23 • Comedy/Animation/Action & Adventure/Kids/Family

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When Blossom and Bubbles get sick, Buttercup volunteers to take care of them for the day.

Where to Stream Episode 21

Season 1 · Episode 21 · Streaming in USA

JustWatch

Episodes

Episode 1
Escape From Monster Island
2016-04-04

Episode 2
Princess Buttercup
2016-04-04

Episode 3
The Stayover
2016-04-05

Episode 4
Painbow
2016-04-06

Episode 5
Horn, Sweet Horn
2016-04-07

Episode 6
Man Up
2016-04-08

Episode 7
Bye Bye Bellum
2016-04-11

Episode 8
Little Octi Lost
2016-04-12

Episode 9
Strong-Armed
2016-04-13

Episode 10
Power-Up Puff
2016-04-14

Episode 11
Tiara Trouble
2016-04-15

Episode 12
The Wrinklegruff Gals
2016-04-21

Episode 13
Arachno-Romance
2016-04-28

Episode 14
Puffdora's Box
2016-05-05

Episode 15
Blue Ribbon Blues
2016-05-12

Episode 16
Frenemy
2016-05-19

Episode 17
Once Upon a Townsville
2016-05-26

Episode 18
Man Up 2: Still Man-ing
2016-05-30

Episode 19
Viral Spiral
2016-06-09

Episode 20
Bubbles of the Opera
2016-06-16

Episode 21
Sister Sitter
2016-06-23

Episode 22
Odd Bubbles Out
2016-09-01

Episode 23
Presidential Punchout
2016-09-08

Episode 24
Cheep Thrills
2016-09-15

Episode 25
Fashion Forward
2016-09-19

Episode 26
In the Garden of Good and Eddie
2016-09-20

Episode 27
Road Trippin'
2016-09-21

Episode 28
The Big Sleep
2016-09-22

Episode 29
The Secret Life of Blossom Powerpuff
2016-09-23

Episode 30
Halt and Catch Silico
2016-10-08

Episode 31
Secret Swapper of Doom
2016-10-15

Episode 32
Rainy Day
2016-10-22

Episode 33
The Squashening
2016-10-27

Episode 34
Electric Buttercup
2016-11-28

Episode 35
Professor Proofed
2016-11-29

Episode 36
Poorbucks
2016-11-30

Episode 37
Snow Month
2016-12-01

Episode 38
Somewhere Over the Swingset
2016-12-02

Episode 39
People Pleaser
2016-12-24

Information

Creator	Bob Boyle
Episode air date	23.06.2016
Episode runtime	11 min
Episode rating	0.00
Genres	Comedy / Animation / Action & Adventure / Kids / Family
TMDB series rating	5.1
IMDb series rating	3.8
Series status	Ended
Age rating	TV-Y7-FV
Country	GW / HK / US

Trailer

Cast

Amanda Leighton

Amanda Leighton
Blossom (voice)

Kristen Li
Bubbles (voice)

Natalie Palamides

Natalie Palamides
Buttercup (voice)

Tom Kane
Professor Utonium (voice)

Tom Kenny
Mayor (voice)

Haley Mancini
Princess Morbucks (voice)

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