Louise, an immortal woman with supernatural origins, finds her love for Charlie tragically complicated. Because of her lineage – she is a descendant of Lilith, the mother of demons – every man she sleeps with dies. Charlie was Louise's first love in the 1920s, whom she unknowingly killed before discovering her true nature. As a descendant of Lilith, Louise's kind must consume the souls of men during each full moon to survive; otherwise, they will die. Now, a century later, Charlie returns reincarnated, forcing Louise to fight her desire for him, lest she doom him once again.